Detailed Abstract
[E-poster]
[E43] Proper position of single and large (≥5 cm) hepatocellular carcinoma in Barcelona clinic liver cancer stage
Hyo-Sin KIM*1
1 Surgery, Chonnam National University School Of Medicine And Hospital, REPUBLIC OF KOREA
Background : The purpose of this study was to evaluate proper position of single large hepatocellular carcinoma (HCC) in Barcelona Clinic Liver Cancer Stage system (BCLC).
Methods : The data was collected from the nationwide multicenter database of the Korean Liver Cancer Association. Patients with single large ( 5cm) HCC was separated from BCLC A group and designated as group X. And remained BCLC Group A was renamed as Group A and BCLC Group B as Group B. Survival outcomes of propensity score-matched groups were compared.
Results : Among the 3965 randomly selected patients, Group X was 414, Group A (2787) and Group B (760). TriMatch analysis allowed us to obtain 116 well-balanced triplets. The 1-,3- and 5-year overall survival rates in the Group X was worse than Group A (91%, 71% and 48% Vs 90%, 78% and 64%, respectively; P<0.000). But it was not different compared to Group B (91%, 71% and 48% Vs 90%, 69% and 48%, respectively; P<0.09). In multivariable analysis, Group X, Group B, Age over 60 years, and prothrombin time international normalized ratio and Creatinine levels were independent predictors of worse overall survival.
Conclusions : Our findings suggest that Group X should be relocated to group BCLC B rather than BCLC A stage.
Methods : The data was collected from the nationwide multicenter database of the Korean Liver Cancer Association. Patients with single large ( 5cm) HCC was separated from BCLC A group and designated as group X. And remained BCLC Group A was renamed as Group A and BCLC Group B as Group B. Survival outcomes of propensity score-matched groups were compared.
Results : Among the 3965 randomly selected patients, Group X was 414, Group A (2787) and Group B (760). TriMatch analysis allowed us to obtain 116 well-balanced triplets. The 1-,3- and 5-year overall survival rates in the Group X was worse than Group A (91%, 71% and 48% Vs 90%, 78% and 64%, respectively; P<0.000). But it was not different compared to Group B (91%, 71% and 48% Vs 90%, 69% and 48%, respectively; P<0.09). In multivariable analysis, Group X, Group B, Age over 60 years, and prothrombin time international normalized ratio and Creatinine levels were independent predictors of worse overall survival.
Conclusions : Our findings suggest that Group X should be relocated to group BCLC B rather than BCLC A stage.
SESSION
E-poster
E-Session 09/16 ALL DAY